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● ARIZONA
PHOENIX
Fred Arnold, DC, NMD

Kent L. Pomeroy, M.D.


SCOTTSDALE
Michael Cronin, N.D.
David Tallman, DC, NMD.


TEMPE
Robb D. Bird, NMD


TUCSON
Jorge B. Cochran, ND.NMD

● ARKANSAS
Merl B. Cox, D.O.

BRITISH COLUMBIA
Christoph Kind, N.D.

CALIFORNIA
ANAHEIM AREA
Hanson Wong, M.D.
Howard Rosen, M.D.

AUBURN
Rodney Van Pelt, M.D.

BAKERSFIELD
Payam Kerendian, D.O.


BEVERLY HILLS
Behzad Emad, M.D.
Payam Kerendian, D.O.


CLOVIS
Kevin Wingert, M.D.

GARDEN GROVE
Howard Rosen, M.D.

GLENDALE
G. Megan Shields, M.D

IRVINE
Allan Sosin, M.D.

Los Angeles
Donna Alderman, D.O.
Marc Darrow, M.D
Hanson Wong, M.D.


Los GATOS
Joshua M, Donaldson, N.D.

Marin County
Paul Handleman, D.O.
John Monagle, NMD


Monterey
Howard Rosen, M.D.


SAN DIEGO
Andrew Kulik, D.O.

Gary Matson, D.O.

SAN FRANCISCO EAST BAY
Donna Alderman, D.O.

SAN FRANCISCO NORTH BAY
Paul Handleman, D.O.
John Monagle, NMD


San Ramon

Richard I. Gracer, M.D.


SANTA BARBARA
Allen Thomashefsky, M.D.


SANTA CRUZ
Joshua M, Donaldson, N.D.

SANTa monica

Peter Fields, M.D.,D.C.

SANTa
ROSA
Justin Hoffman, NMD

Temecula
Edward A. Venn-Watson, M.D.

UKIAH AREA
Rodney Van Pelt, M.D.

● COLORADO
BOULDER
Gary Clark, M.D.


BROOMFIELD

Christopher J. Centeno, M.D.
John R. Schultz, M.D.


COLORADO SPRINGS
Mary Harrow, D.O,

DENVER
Joel A. Berenbeim, D.O.
Thomas Ravin, M.D.

FORT COLLINS
Mark Kelley, N.D. LAc

LITTLETON
Jo Ann Douglas, M.S.,D.O

PARKER
John A. Littleford, D.O.

STEAMBOAT SPRINGS
Jon Freckleton, D.O.

● CONNECTICUT
AVON
Valley Sports Physicians & Orthopedic Medicine
Paul Tortland, D.O.
Albert Kozar

WEST REDDING

Perry M. Perretz, D.O.

● DELAWARE
SOUTHERN NJ
Scott R. Greenberg, M.D.
SOUTHERN PA
Brian J. Shiple, D.O.

● FLORIDA
ORLANDO AREA
Nelson Kraucak, M.D.


ORMAND BEACH
Hana Chaim, DO

Clearwater
Felix Linetsky, M.D.

PLANTATION
Alvin Stein,M.D.

SARASOTA/TAMPA BAY
Mark Walter, M.D.
Wellington Chen, M.D.
Matthew Burks, M.D.

TAMPA BAY AREA
Felix Linetsky, M.D.
Robinson Family Clinic

● GEORGIA
WARNER ROBINS
E. Glynn Taunton, D.O.

MARIETTA
Robert C. Shuman, M.D.


● HAWAII
HAIKU
Kevin Davison, N.D.

HILO

Liza Maniquis-Smigel, MD

Honolulu, Hawaii
Liza Maniquis-Smigel, MD

● ILLINOIS
CHICAGOLAND

Ross Hauser, M.D

PEORIA
Yibing Li, M.D.
Jay Harms, M.D.

WESTERN ILLINOIS
Anwer Rasheed, M.D.

● INDIANA
CLARKSVILLE
Steven M. Johnson, D.O.

LAFAYETTE

Carolyn G. Kochert, M.D.

Mishawaka
Mark S. Cantieri, D.O.,

● IOWA
CLINTON
Anwer Rasheed, M.D.
IOWA CITY
John Macatee, DO.
WEST DES MOINES
Jacqueline M Stoken, D.O

● KANSAS
KANSAS CITY AREA

K. Dean Reeves, M.D.

TOPEKA
Doug Frye, M.D.

● KENTUCKY
LOUISVILLE
Steven M. Johnson, D.O.

● LOUISIANA
NEW ORLEANS AREA
Thomas K. Bond, M.D.

● MARYLAND
Rockville
Ingrid Gheen, M.D.

● MASSACHUSETTS
MALDEN
Albert V. Franchi, M.D.
WORCESTER

Jon Trister, M.D.

● MICHIGAN
Howell

Jerald Gach, DO
SHELBY TWP
Robert Krasnick, M.D.
Southfield

Jerald Gach, DO
WARREN

Robert Krasnick, M.D.

● MINNESOTA
EXCELSIOR/Menahga
Mark T. Wheaton, M.D.


MINNETONKA
George H. Kramer, M.D.


● MISSOURI
KANSAS CITY
Edward McDonagh, D.O

ST. Peters
Michael J. Adams


● MONTANA
HAMILTON
Mark Kelley, N.D. LAc

● NEVADA
CARSON CITY

Alfred N. Grimes, M.D.


RENO
Andrew C. Wesely, M.D.

● NEW JERSEY
BLAIRSTOWN
Walter R. Grote, D.O

CENTRAL NJ
Edward Magaziner, M.D.

WAYNE/NORTH NJ
Robert Kramberg, M.D.

SOUTH NJ/
PHILADELPHIA
Scott R. Greenberg, M.D.
(Cherry Hill)

Joseph P. Mullane, M.D.
(Hamilton)


Brian J. Shiple, D.O.
(Springfield PA)

● NEW MEXICO
Albuquerque

R. Dean Bair, D.O.

James E. Baum, D.O.
SANTA FE
James E. Baum, D.O.

Jonas R. Skardis, DOM

● NEW YORK
B
ALDWIN
Pandu Tadoori, M.D.

BUFFALO AREA
Timothy L. Speciale, D.O.
BROOKLYN
Neil Raff, MD, CNS
David Zirkitev, P.A.
EAST MEADOW

Christopher Calapai, D.O.

FLUSHING
Neil Raff, MD, CNS
HICKSVILLE
David Borenstein, M.D.

MANHATTAN
Richard Ash, M.D.
David Borenstein, M.D.
John H. Juhl, D.O.
Robert Kramberg, M.D.
NEW YORK METRO AREA
Perry M. Perretz, D.O.
Edward Magaziner, M.D.
Scott R. Greenberg, M.D.
ORANGE
Neil Raff, MD, CNS
ROCKLAND
Neil Raff, MD, CNS
WESTMINSTER
Neil Raff, MD, CNS

● NORTH CAROLINA
ASHEVILLE AREA

Stephen Blievernicht, M.D.
CARY

Catherine Duncan, D.O.

Huntersville
Dr. Mark Hines

● OHIO
AKRON/CANTON
Vladimir Djuric, M.D.
BLUFFTON

L. Terry Chappell, M.D.
CENTERVILLE
Rick Buenaventura, M.D.
CINCINNATI
Michael J. Bertram, MD

TOLEDO AREA

Jay W. Nielsen, M.D.

● OKLAHOMA
BROKEN ARROW
Shirley J. Welden, M.D.

● OREGON
ASHLAND
Allen Thomashefsky,M.D.
EUGENE
Thomas Peterson, M.D.
HILLSBORO
Kevin C. Wilson, N.D.

LAKE OSWEGO

Noel S. Peterson, N.D.

MEDFORD
Carl Osborn, D.O.
OREGON CITY
Joanne Gordon, ND,MS,PT

PORTLAND

Rick Marinelli, N.D.

Chiaoli Lu, ND. LAc. DAOM.
Patrick Chapman, N.D.
Joshua David, N.D.
REDMOND
E. Payson Flattery, D.C.,N.D.
SALEM
Donald McBride, Jr, ND


● PENNSYLVANIA
BALA CYNWYD
Harvey Kleinberg, D.O.
BETHLEHEM
James F. Frommer, M.D.
ELKINS PARK
Kab S. Hong, M.D.
JEANNETTE
Martin P. Gallagher, M.D., D.C.
MEADVILLE
Paul Peirsel, M.D.
PITTSBURG

Paul S. Lieber, MD
SOUTHERN NJ - PA
Scott R. Greenberg, M.D.
Allan Magaziner, D.O
Edward Magaziner, M.D.
SPRINGFIELD
Brian J. Shiple, D.O.
WOMELSDORF
Peter J Blakemore, D.O,

● SOUTH CAROLINA
GREENVILLE/SPARTANSBURG 
Robert Schwartz, M.D.
CHARLESTON
Marc N. Dubick, M.D.
MOUNT PLEASANT
Patrick Lovegrove, D.O.

● TENNESSEE
BRENTWOOD
Mark L. Johnson, M.D.
CLARKSVILLE
Rafael Prieto, M.D.
JACKSON
Marcus E. Meekins, M.D.
MEMPHIS
Marcus E. Meekins, M.D.
NASHVILLE
Mark L. Johnson, M.D.

● TEXAS
AUSTIN
Mihnea Dumitrescu, M.D.

David K. Harris, M.D.
Brad Fullerton, M.D.
DALLAS
Michael Ellman, M.D.

DENTON
Carlos J. Garcia, M.D.
FORT WORTH
Gerald Harris, DO
Dennis E. Minotti II, D.O
David E. Teitelbaum, D.O.
HOUSTON
Robert Battle, M.D.
Adam Weglein, D.O
HOUSTON AREA

Joseph G. Valdez, M.D

John P. Trowbridge
MESQUITE
Michael Ellman, M.D.
PARIS
Gregg Diamond, M.D.
Norberto Vargas, M.D.
PLANO
Michael Ellman, M.D.
RICHARDSON
Gregg Diamond, M.D.
Norberto Vargas, M.D.

SAN ANTONIO
Annette M. Zaharoff, M.D.
SHERMAN
Gregg Diamond, M.D.
Norberto Vargas, M.D.
SUNNYVALE
Gregg Diamond, M.D.
Norberto Vargas, M.D.

TOMBALL
Shaun Lehmann, M.D.
Curtis Fandrich, D.O.


● UTAH
PARK CITY
Harry Adelson, N.D.
Kenneth Hurwitz, M.D.
SALT LAKE CITY
Harry Adelson, N.D.
E. Alan Jeppsen
SPANISH FORK
David Taylor Roberts, M.D

● VERMONT
WINOOSKI
Jonathan E. Fenton, D.O

● VIRGINIA
ALEXANDRIA
Robert H. Wagner, M.D.
BLUEFIELD
Lenny Horwitz, DPM
FAIRFAX
Mayo Friedlis, M.D.
McLEAN
David Wang, D.O.

VIRGINIA BEACH
Lisa Barr, M.D.

● WASHINGTON
ISSAQUAH
Jena Schliiter., M.D.

SEATTLE AREA
Richard A. Sandler, M.D.
JoAnna Forwell, N.D.

Adam R. Geiger, N.D.


● WEST VIRGINIA
MORGANTOWN

Nori Onishi, D.O.


● WISCONSIN
EAU CLAIRE
Deborah Raehl, DO

WAUWATOSA
Neal Pollack, D.O.

MILWAUKEE
William J. Faber, D.O.
 

The History of Prolotherapy
Ross Hauser, M.D.
 

The concept of Prolotherapy originated in the non-surgical treatment of hernias, varicose veins, and hemorrhoids, all conditions which are due to connective tissue weakness. If the connective tissue in the veins becomes weakened, hemorrhoids and varicose veins form. Weakness in the collagen, of course, causes Ligament laxity and tendon degeneration with resultant chronic pain. Most of the early innovators in injection treatment method were surgeons who were looking for methods to improve surgical outcomes or replace surgery with more conservative methods. The injection of hernias, varicose veins, and hemorrhoids was called Sclerotherapy, because the injection "sclerosed," or scarred, the area.
 

Celsus, a Roman encyclopedist and not a physician, described the earliest application of Sclerotherapy in the first century B.C. Saltpeter (Potassium nitrate) was injected to treat hydrocele (accumulation of fluid around the testicle). The instrument and method of injection was, however, not described. Seventeen centuries later, Samuel Sharp, a surgeon at Guy's Hospital, the oldest teaching hospital of the University of London Medical School, began treating hydrocele by Sclerotherapy and started training others.
 

The Research and Growth of Prolotherapy

In January 1938, Arthur Steindler and J. V. Luck published a fundamental work related to the diagnosis of lower back pain based on procaine injections. They provided strong evidence that all structures in the lower back, including the ligaments, fascia, tendons, and muscles, receive sensory nerve impulses. They pointed out that these structures are all interrelated anatomically and functionally, and they came up with a list of criteria that had to be met to prove that an injured structure was causing a pain symptom.
 

This work was monumental in the history of Prolotherapy. Now a method to definitely prove what was causing the pain existed. A person came to the physician with low back pain radiating to the legs. The doctor, with a needle, then tried to exactly reproduce the pain and the radiating pain down the leg. When the exact site was found, an injection of procaine was given. If the correct structures were injected, all of the pain would be completely removed. The latter part of this concept is followed to this day. Prolotherapy can completely remove chronic pain immediately, if the correct structures have been injected, because of the anesthetic part of the solution.
 

The First Prolotherapy Treatment

In 1937, Dr. Louis W. Schultz, both a dentist and a medical doctor, published a paper in The Journal of the American Medical Association on the treatment of subluxation of the temporomandibular joint (TMJ). In this paper he described how common TMJ syndrome was, and that the traditional treatments of rest, appliances in the mouth, physical therapy, and surgery were only partially successful. He described a simple method of shortening and strengthening the TMJ capsule by injection of Sylnasol, a five percent solution of fatty acid. This was the first true Prolotherapy treatment. Dr. Schultz collected extensive data from both animal research and clinical practice , and concluded that the method he discovered was simple, safe, and essentially 100 percent effective.
 

The Development of Prolotherapy as a Cure for Chronic Pain

George S. Hackett, M.D. is considered one of the pioneers, or founders, of modern day Prolotherapy because he brought this technique to mainstream medicine. His research was published in some of the main medical journals of his time and presented at the prestigious American Medical Association meetings. Some of the statistics on his research include:

Sample size: 656 patients
Patient age range: 15 to 88 years old
Duration of pain: three months to 65 years
Average duration of symptoms: four and a half years
Duration of study: 19 years
Number of injections given: 18,000

Dr. Hackett did a remarkable job in that he followed his patients for 12 years after the prolotherapy treatments were completed. Twelve years after treatment, an impressive 82 percent of the patients considered themselves cured. Dr. Hackett believed that the cure rate was actually over 90 percent, due to improvements in the technique over the years. He used Sylnasol, a fatty acid, as the proliferant, which is no longer available. Later proponents of the Hackett technique of Prolotherapy found that a simple dextrose solution diluted with local anesthetics was as effective as the Sylnasol, and solutions such as this are still used today. Dr. Hackett also proved in the laboratory that Prolotherapy induces the growth of ligament and tendon tissue and is especially effective at strengthening the weld of these structures to the bone, by proliferating their fibro-osseous junction.
 

In 1955, at an American Medical Association meeting, Dr. Gustav Hemwall was astonished to see so many doctors at one particular exhibit. The presenter was talking about a very successful treatment for chronic low back pain. Nothing was worse at the time for Dr. Hemwall than having a chronic low back pain patient come to him, because the treatments he was able to offer were not very successful. The doctor doing the presentation was George S. Hackett, M.D., and he was discussing the technique of Prolotherapy.
 

Once the crowd diminished, Dr. Hemwall asked Dr. Hackett how he could learn the treatment described in his book, Ligament and Tendon Relaxation Treated by Prolotherapy. Dr. Hemwall went to Dr. Hackett's office in Canton, Ohio, to learn the technique. Dr. Hemwall became so proficient at administering the technique that Dr. Hackett would later refer patients to him.
 

Prolotherapy owes a great debt to Dr. Hemwall. Between 1955 until his retirement in 1996, he was the main instructor and proponent of Prolotherapy in the United States. He was not a researcher but a clinician, and perhaps the world's greatest Prolotherapy doctor. He treated more than 10,000 patients world wide and collected data on 8,000 of these patients. In 1974, Dr. Hemwall presented his largest survey of 2,007 Prolotherapy patients to the Prolotherapy Association. The survey related the following:

1,871 patients completed treatment
6,000 treatments were administered
1,399 (75.5 percent) patients reported recovery and cure
413 (24.3 percent) reported general improvement
25 (0.2 percent) patients showed no improvements
170 patients were lost to follow up.

More than 99 percent of the patients who completed treatment with Prolotherapy found relief from their chronic pain. These results are similar to those published by Dr. Hackett, showing that Prolotherapy is completely curative in many cases (75 to 90 percent) and provides some pain relief in nearly all patients treated.

At the age of 87, in June of 1996, Gustav A. Hemwall M.D. electively retired from the practice of medicine and turned over the helm of his private practice to Dr. Ross Hauser. He had been on the medical staff of West Suburban Hospital in Oak Park, Illinois for 60 years.


The opinions expressed here does not necessarily reflect the views of the other member physicians of getprolo.com.

Prolotherapy
Information and Research
Prolotherapy
Prolotherapy
How Does Prolotherapy Work?
Why Does Prolotherapy Work?
How Prolotherapy Helps?
Indications - Contraindications
Introduction to Prolotherapy
Why Get Prolotherapy?
What is Prolotherapy?
How Does Prolotherapy Work?
Are You A Prolo Candidate?

Ligament Reconstruction
How Safe Is Prolotherapy?
Finding a Prolotherapy doctor
When Prolo May Not Work
20 Questions - Prolotherapy
The History of Prolotherapy
Curing Chronic Pain
Sclerotherapy?
Turning to Prolotherapy
Prolotherapy and Chronic Pain
Proof Prolotherapy is Working
Creating Collagen
How To Support Treatment

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Prolotherapy and Inflammation

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The Journal of Prolotherapy


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A medical testimonial is intended to represent that everyone will obtain the same favorable results from a given therapy. Getprolo.com disclaims any such intention. 

Prolotherapy is a medical technique. As with any medical technique, results will vary among individuals. Prolotherapy injections may not work for you and as with all medical procedures there are risks involved. These risks should be discussed with a qualified health care professional prior to any treatment.

This Prolotherapy information is offered for educational purposes only. Do not act or rely upon the information on this website without seeking independent professional medical advice. 

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