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Prolotherapy Doctor
Physicians Add Your
Listing
● ARIZONA
PHOENIX
Fred Arnold, DC, NMD
Kent L.
Pomeroy, M.D.
SCOTTSDALE
Michael Cronin, N.D.
David Tallman, DC, NMD.
TEMPE
Robb D.
Bird, NMD
TUCSON
Jorge B. Cochran, ND.NMD
● ARKANSAS
Merl
B. Cox, D.O.
●
BRITISH COLUMBIA
Christoph Kind, N.D.
●
CALIFORNIA
ANAHEIM
AREA
Hanson
Wong, M.D.
Howard Rosen,
M.D.
AUBURN
Rodney Van Pelt, M.D.
BAKERSFIELD
Payam Kerendian, D.O.
BEVERLY HILLS
Behzad Emad, M.D.
Payam Kerendian, D.O.
CLOVIS
Kevin Wingert, M.D.
GARDEN GROVE
Howard Rosen,
M.D.
GLENDALE
G. Megan Shields, M.D
IRVINE
Allan
Sosin, M.D.
Los Angeles
Donna Alderman,
D.O.
Marc Darrow, M.D
Hanson
Wong, M.D.
Los
GATOS
Joshua M, Donaldson, N.D.
Marin County
Paul
Handleman, D.O.
John Monagle, NMD
Monterey
Howard Rosen,
M.D.
SAN
DIEGO
Andrew
Kulik, D.O.
Gary Matson, D.O.
SAN FRANCISCO EAST BAY
Donna Alderman,
D.O.
SAN FRANCISCO NORTH BAY
Paul
Handleman, D.O.
John Monagle, NMD
San
Ramon
Richard I.
Gracer, M.D.
SANTA
BARBARA
Allen
Thomashefsky, M.D.
SANTA
CRUZ
Joshua M, Donaldson, N.D.
SANTa monica
Peter Fields, M.D.,D.C.
SANTa
ROSA
Justin Hoffman, NMD
Temecula
Edward A.
Venn-Watson, M.D.
UKIAH
AREA
Rodney Van Pelt, M.D.
● COLORADO
BOULDER
Gary Clark, M.D.
BROOMFIELD
Christopher J. Centeno, M.D.
John
R. Schultz, M.D.
COLORADO SPRINGS
Mary Harrow, D.O,
DENVER
Joel A. Berenbeim, D.O.
Thomas Ravin, M.D.
FORT COLLINS
Mark Kelley, N.D. LAc
LITTLETON
Jo
Ann Douglas, M.S.,D.O
PARKER
John
A. Littleford, D.O.
STEAMBOAT SPRINGS
Jon Freckleton, D.O.
● CONNECTICUT
AVON
Valley Sports Physicians & Orthopedic
Medicine
Paul Tortland, D.O.
Albert Kozar
WEST
REDDING
Perry M.
Perretz, D.O.
● DELAWARE
SOUTHERN NJ
Scott R. Greenberg, M.D.
SOUTHERN PA
Brian J.
Shiple, D.O.
● FLORIDA
ORLANDO AREA
Nelson Kraucak, M.D.
ORMAND BEACH
Hana Chaim, DO
Clearwater
Felix Linetsky, M.D.
PLANTATION
Alvin Stein,M.D.
SARASOTA/TAMPA BAY
Mark Walter, M.D.
Wellington Chen, M.D.
Matthew Burks, M.D.
TAMPA BAY AREA
Felix Linetsky, M.D.
Robinson Family Clinic
● GEORGIA
WARNER ROBINS
E.
Glynn Taunton, D.O.
MARIETTA
Robert C. Shuman, M.D.
● HAWAII
HAIKU
Kevin Davison, N.D.
HILO
Liza Maniquis-Smigel, MD
Honolulu, Hawaii
Liza Maniquis-Smigel, MD
● ILLINOIS
CHICAGOLAND
Ross Hauser, M.D
PEORIA
Yibing
Li, M.D.
Jay Harms,
M.D.
WESTERN ILLINOIS
Anwer Rasheed, M.D.
● INDIANA
CLARKSVILLE
Steven
M. Johnson, D.O.
LAFAYETTE
Carolyn
G. Kochert, M.D.
Mishawaka
Mark S. Cantieri, D.O.,
● IOWA
CLINTON
Anwer Rasheed, M.D.
IOWA CITY
John
Macatee, DO.
WEST DES MOINES
Jacqueline M Stoken, D.O
● KANSAS
KANSAS
CITY AREA
K. Dean Reeves, M.D.
TOPEKA
Doug Frye, M.D.
● KENTUCKY
LOUISVILLE
Steven
M. Johnson, D.O.
● LOUISIANA
NEW ORLEANS AREA
Thomas K. Bond, M.D.
● MARYLAND
Rockville
Ingrid Gheen, M.D.
● MASSACHUSETTS
MALDEN
Albert V. Franchi, M.D.
WORCESTER
Jon Trister, M.D.
● MICHIGAN
Howell
Jerald Gach, DO
SHELBY TWP
Robert Krasnick,
M.D.
Southfield
Jerald Gach, DO
WARREN
Robert Krasnick,
M.D.
● MINNESOTA
EXCELSIOR/Menahga
Mark T. Wheaton, M.D.
MINNETONKA
George H. Kramer, M.D.
● MISSOURI
KANSAS CITY
Edward McDonagh, D.O
ST. Peters
Michael J.
Adams
● MONTANA
HAMILTON
Mark Kelley, N.D. LAc
● NEVADA
CARSON CITY
Alfred N.
Grimes, M.D.
RENO
Andrew C.
Wesely, M.D.
● NEW JERSEY
BLAIRSTOWN
Walter R. Grote, D.O
CENTRAL NJ
Edward Magaziner, M.D.
WAYNE/NORTH NJ
Robert
Kramberg, M.D.
SOUTH NJ/PHILADELPHIA
Scott R. Greenberg, M.D.
(Cherry Hill)
Joseph P. Mullane, M.D.
(Hamilton)
Brian J.
Shiple, D.O.
(Springfield PA)
●
NEW MEXICO
Albuquerque
R. Dean Bair, D.O.
James
E. Baum,
D.O.
SANTA FE
James
E. Baum,
D.O.
Jonas R. Skardis, DOM
● NEW YORK
BALDWIN
Pandu Tadoori, M.D.
BUFFALO AREA
Timothy L. Speciale, D.O.
BROOKLYN
Neil Raff, MD, CNS
David Zirkitev,
P.A.
EAST MEADOW
Christopher Calapai, D.O.
FLUSHING
Neil Raff, MD, CNS
HICKSVILLE
David Borenstein, M.D.
MANHATTAN
Richard Ash, M.D.
David Borenstein, M.D.
John H. Juhl, D.O.
Robert Kramberg, M.D.
NEW YORK METRO AREA
Perry M. Perretz, D.O.
Edward Magaziner, M.D.
Scott R. Greenberg, M.D.
ORANGE
Neil Raff, MD, CNS
ROCKLAND
Neil Raff, MD, CNS
WESTMINSTER
Neil Raff, MD, CNS
● NORTH CAROLINA
ASHEVILLE AREA
Stephen
Blievernicht, M.D.
CARY
Catherine Duncan, D.O.
Huntersville
Dr. Mark Hines
● OHIO
AKRON/CANTON
Vladimir Djuric, M.D.
BLUFFTON
L. Terry Chappell, M.D.
CENTERVILLE
Rick
Buenaventura, M.D.
CINCINNATI
Michael J. Bertram, MD
TOLEDO
AREA
Jay W. Nielsen, M.D.
● OKLAHOMA
BROKEN ARROW
Shirley J.
Welden, M.D.
● OREGON
ASHLAND
Allen
Thomashefsky,M.D.
EUGENE
Thomas
Peterson, M.D.
HILLSBORO
Kevin C. Wilson, N.D.
LAKE OSWEGO
Noel S. Peterson, N.D.
MEDFORD
Carl Osborn, D.O.
OREGON CITY
Joanne Gordon, ND,MS,PT
PORTLAND
Rick Marinelli, N.D.
Chiaoli
Lu, ND. LAc. DAOM.
Patrick Chapman, N.D.
Joshua David,
N.D.
REDMOND
E. Payson Flattery, D.C.,N.D.
SALEM
Donald McBride, Jr, ND
● PENNSYLVANIA
BALA CYNWYD
Harvey Kleinberg, D.O.
BETHLEHEM
James F. Frommer, M.D.
ELKINS PARK
Kab S. Hong, M.D.
JEANNETTE
Martin
P. Gallagher, M.D., D.C.
MEADVILLE
Paul Peirsel,
M.D.
PITTSBURG
Paul S. Lieber, MD
SOUTHERN NJ - PA
Scott R. Greenberg, M.D.
Allan Magaziner, D.O
Edward Magaziner, M.D.
SPRINGFIELD
Brian J.
Shiple, D.O.
WOMELSDORF
Peter J Blakemore, D.O,
● SOUTH CAROLINA
GREENVILLE/SPARTANSBURG
Robert Schwartz, M.D.
CHARLESTON
Marc N.
Dubick, M.D.
MOUNT PLEASANT
Patrick
Lovegrove, D.O.
● TENNESSEE
BRENTWOOD
Mark L.
Johnson, M.D.
CLARKSVILLE
Rafael Prieto, M.D.
JACKSON
Marcus
E. Meekins, M.D.
MEMPHIS
Marcus
E. Meekins, M.D.
NASHVILLE
Mark L.
Johnson, M.D.
● TEXAS
AUSTIN
Mihnea Dumitrescu, M.D.
David
K. Harris, M.D.
Brad Fullerton, M.D.
DALLAS
Michael Ellman, M.D.
DENTON
Carlos
J. Garcia, M.D.
FORT
WORTH
Gerald Harris, DO
Dennis E. Minotti II, D.O
David E. Teitelbaum, D.O.
HOUSTON
Robert Battle, M.D.
Adam Weglein,
D.O
HOUSTON AREA
Joseph
G. Valdez, M.D
John P. Trowbridge
MESQUITE
Michael Ellman, M.D.
PARIS
Gregg
Diamond, M.D.
Norberto Vargas, M.D.
PLANO
Michael Ellman, M.D.
RICHARDSON
Gregg
Diamond, M.D.
Norberto Vargas, M.D.
SAN ANTONIO
Annette M. Zaharoff,
M.D.
SHERMAN
Gregg
Diamond, M.D.
Norberto Vargas, M.D.
SUNNYVALE
Gregg
Diamond, M.D.
Norberto Vargas, M.D.
TOMBALL
Shaun Lehmann, M.D.
Curtis Fandrich, D.O.
● UTAH
PARK CITY
Harry Adelson, N.D.
Kenneth Hurwitz, M.D.
SALT LAKE CITY
Harry Adelson, N.D.
E. Alan Jeppsen
SPANISH FORK
David Taylor Roberts, M.D
● VERMONT
WINOOSKI
Jonathan
E. Fenton, D.O
● VIRGINIA
ALEXANDRIA
Robert H. Wagner,
M.D.
BLUEFIELD
Lenny
Horwitz, DPM
FAIRFAX
Mayo
Friedlis, M.D.
McLEAN
David Wang, D.O.
VIRGINIA BEACH
Lisa
Barr, M.D.
● WASHINGTON
ISSAQUAH
Jena
Schliiter., M.D.
SEATTLE
AREA
Richard
A. Sandler, M.D.
JoAnna Forwell, N.D.
Adam R.
Geiger, N.D.
● WEST VIRGINIA
MORGANTOWN
Nori Onishi, D.O.
● WISCONSIN
EAU CLAIRE
Deborah Raehl, DO
WAUWATOSA
Neal Pollack, D.O.
MILWAUKEE
William
J. Faber, D.O.
|
 PROLOTHERAPY IS A GREAT ALTERNATIVE
TREATMENT FOR TENDON DAMAGE FROM FLUOROQUINOLONES ANTIBIOTICS
Ross Hauser, M.D.
As if there isn’t enough pain out there, now scientists have learned
that fluoroquinolone antibiotics damage
tendons. Yes, you can get
wake up one day and all of a sudden you have pain in or around a joint
just because you took an antibiotic.
Dick came to
Caring
Medical because of a severe left
shoulder
pain.
There was no precipitating event except that he needed several rounds of
Levoquin for a urinary infection because of a urethral stricture. On
physical examination he had evidence of a
supraspinatous tendinopathy
(Rotator Cuff)
which now was causing a
frozen shoulder (adhesive
capsulitis). Fortunately for Dick he came in early and only necessitated
two
prolotherapy treatments one month apart. He also received aggressive
Physical therapy for the limitation of
shoulder range of motion. Within
six weeks of therapy he was back to swimming. He made a full recovery.
To show you the extent of damage that can occur with fluoroquinolones, a
client named Amy came to Caring Medical convinced she had tendon and
muscle injury from the antibiotics she took. She explained, “I had a
respiratory infection so I was given Levoquin. After the infection was
over I had pain all over my body and it hasn’t stopped!” After
questioning Amy and examining here we did some blood work. She did not
have Candida, but did have a high CPK level which can indicate muscle
damage. I am now convinced that Amy was correct, she did get muscle and
tendon damage all over her body from the fluoroquinolone antibiotic she
received. She will soon be in for her second visit.
Fluoroquinolones are a class of synthetic antibiotics which have a broad
spectrum of antibiotic activity that includes both Gram negative and
Gram positive bacteria. Some of the more common ones are Levoquin (levofloxacin),
Ciproxin (ciprofloxacin) other common drug names are Baloxin and Tequin,
and common chemical names are enoxacin, lomefloxacin and norfloxacin. In
the literature many side effects have been documented including
tendinitis and subsequent tendon rupture. The incidence is felt to be
between 0.14%-0.4% but if someone has other health conditions, the
incidence can go up to 15.6%. Advanced age seems to be the most
significant risk factor. Long periods of hemodialysis, diabetes
mellitus, hyperparathyroidism, rheumatic diseases, gout, and
corticosteroids are other predisposing factors.1,2
To investigate the cause of tendon injury, researchers at the University
of Berlin, Germany incubated human tendon cells with differing
concentrations of ciprofloxacin and levoquin. They then looked at the
cells under an electron microscope. At concentrations which are
achievable during quinolone therapy, tendon synthesis of collagen was
significantly decreased. The inhibition was dose-dependent. Effects were
intensified at higher concentrations and longer incubation periods. If
this isn’t bad enough, the researchers found that both fluoroquinolones
induced apoptosis in the cells. Apoptosis means programmed cell death.
This was confirmed by electron microscopy. In other words,
fluroquinolones can cause the tendon cells to die prematurely! Their
conclusion reads as follows: ‘Our results provide evidence that besides
changes in receptor and signaling proteins apoptosis has to be
considered as a final event in the pathogenesis of fluoroquinolone-induced
tendinopathies’.3
Summary
What’s it all about, Alfie? Sometimes strong medications are needed. The
doctor and patient must evaluate the risks and benefits before starting
any theray. Fluoroquinolones are strong antibiotics. When they are
prescribed, the doctor and user must be aware that tendon injury is a
possibility. For those suffering from chronic tendon injuries, a
treatment to consider is
Prolotherapy. Prolotherapy stimulates the body
to repair painful areas, such as tendon and ligament injuries.
Prolotherapy to the injured tendon will induce a mild inflammatory
reaction which is the body’s mechanism to repair injured areas.
Prolotherapy causes a proliferation (thus the word prolo-) of the
fibroblasts which make the collagen which makes up the ligament or
tendon. Typically three to six sessions at four to six week intervals is
the usual course. If you or someone you know and love has
fluoroquinolone-induced tendon injury, tell them about Prolotherapy.
Prolotherapy offers hope for people with this condition.
References:
1. Muzi F, Gravante G, Tati E, Tati G. Fluoroquinolones-induces
tendinitis and tendon rupture in kidney transplant recipients: 2 cases
and a review of literature. Transplantation Proceedings . 2007;
39:1673-1675.
2. Kempka G, Ahr HJ, Ruther W, Schluter G. Effects of fluoroquinolones
and glucocorticoids on cultivated tendon cells in vitro. Toxicology in
Vitro. 1996;10:743-754.
3. Sendzik J, Shakibaei M, Schafer-Korting M, Stahlmann R.
Fluoroquinolones cause changes in extracellular matrix, signaling
proteins, metalloproteinases and caspase-3 in cultured human tendon
cells. Toxicology. 2005;212:24-36.
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Prolotherapy
Information and Research
Prolotherapy
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Prolotherapy
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Does Prolotherapy Work?
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Does Prolotherapy Work?
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Prolotherapy Helps?
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Work
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Support Treatment
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